Gemifloxacin is used to treat bacterial infections, particularly respiratory tract infections such as acute bronchitis and pneumonia caused by susceptible microorganisms. It is effective against a broad range of bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Due to its strong activity against both common and atypical respiratory pathogens like Mycoplasma pneumoniae and Chlamydophila pneumoniae, it is often prescribed for community-acquired pneumonia. The compound achieves high concentrations in lung tissue and epithelial lining fluid, enhancing its effectiveness at the site of infection. Its use is generally reserved for cases where other antibiotics may not be suitable or effective.