Cleroindicin D exhibits significant antimicrobial activity, particularly against Gram-positive bacteria, making it a candidate for development in anti-infective therapies. It has also shown cytotoxic effects against certain cancer cell lines, suggesting potential in oncology for targeting tumor cells. Studies indicate mechanisms involving inhibition of cell wall synthesis or disruption of microbial membrane function. Due to its natural origin and unique structure, it is studied for use in structure-based drug design to create more potent derivatives. Currently, it has no commercial or medical applications but shows promise as a starting material for new drugs. Additionally, Cleroindicin D serves as a biochemical tool in research to probe bacterial enzyme functions and resistance mechanisms.