1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
97%
Reagent
Code: #121021
CAS Number
154093-72-8
science Other reagents with same CAS 154093-72-8
blur_circular Chemical Specifications
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Molecular Information
Weight
281.21 g/mol
Formula
C₁₃H₉F₂NO₄
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Registry Numbers
MDL Number
MFCD25973506
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Storage & Handling
Storage
Room temperature, dry and sealed
description Product Description
This compound is primarily utilized in the development of antibacterial agents, particularly fluoroquinolone antibiotics. It serves as a key intermediate in the synthesis of drugs that target bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication. The structural features of this compound, including the cyclopropyl and difluoro groups, enhance its ability to penetrate bacterial cells and improve its binding affinity to target enzymes. Its application is significant in creating broad-spectrum antibiotics effective against both Gram-positive and Gram-negative bacteria, making it valuable in treating respiratory, urinary tract, and gastrointestinal infections. Additionally, its role in combating antibiotic-resistant strains of bacteria highlights its importance in modern medicinal chemistry.
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