1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

97%

Reagent Code: #121021
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CAS Number 154093-72-8

science Other reagents with same CAS 154093-72-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 281.21 g/mol
Formula C₁₃H₉F₂NO₄
badge Registry Numbers
MDL Number MFCD25973506
inventory_2 Storage & Handling
Storage Room temperature, dry and sealed

description Product Description

This compound is primarily utilized in the development of antibacterial agents, particularly fluoroquinolone antibiotics. It serves as a key intermediate in the synthesis of drugs that target bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication. The structural features of this compound, including the cyclopropyl and difluoro groups, enhance its ability to penetrate bacterial cells and improve its binding affinity to target enzymes. Its application is significant in creating broad-spectrum antibiotics effective against both Gram-positive and Gram-negative bacteria, making it valuable in treating respiratory, urinary tract, and gastrointestinal infections. Additionally, its role in combating antibiotic-resistant strains of bacteria highlights its importance in modern medicinal chemistry.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,385.00
inventory 1g
10-20 days ฿4,761.00
inventory 5g
10-20 days ฿14,049.00

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1-Cyclopropyl-6,7-difluoro-8-hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
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This compound is primarily utilized in the development of antibacterial agents, particularly fluoroquinolone antibiotics. It serves as a key intermediate in the synthesis of drugs that target bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication. The structural features of this compound, including the cyclopropyl and difluoro groups, enhance its ability to penetrate bacterial cells and improve its binding affinity to target enzymes. Its application is significant in creating broad-spectrum antibiotics effective against both Gram-positive and Gram-negative bacteria, making it valuable in treating respiratory, urinary tract, and gastrointestinal infections. Additionally, its role in combating antibiotic-resistant strains of bacteria highlights its importance in modern medicinal chemistry.
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