Zabofloxacin hydrochloride is primarily used as a broad-spectrum antibiotic, effective against both Gram-positive and Gram-negative bacteria. It is commonly applied in the treatment of respiratory tract infections, including community-acquired pneumonia and acute bacterial exacerbations of chronic bronchitis. Its mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, which prevents bacterial DNA replication and transcription, leading to cell death. Due to its potent antibacterial activity, it is also being explored for use in treating skin and soft tissue infections. Additionally, its efficacy against drug-resistant bacterial strains makes it a valuable option in combating antibiotic-resistant infections.