8-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline
98%
Reagent
Code: #187090
Alias
8-fluoro-4-hydroxy-2-trifluoromethylquinoline; 2-trifluoromethyl-4-hydroxy-8-fluoroquinoline
CAS Number
31009-31-1
blur_circular Chemical Specifications
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Molecular Information
Weight
231.15 g/mol
Formula
C₁₀H₅F₄NO
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Registry Numbers
MDL Number
MFCD00276580
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Physical Properties
Melting Point
111 °C
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, enhancing antimicrobial activity against resistant bacterial strains. Its structure supports improved cell penetration and binding to DNA gyrase and topoisomerase IV enzymes. Also explored in agrochemicals for developing herbicides and fungicides due to its stability and bioactivity. Shows potential in medicinal chemistry for targeting central nervous system disorders owing to its ability to cross the blood-brain barrier.
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