Ethyl 8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylate
98%
Reagent
Code: #184471
CAS Number
31602-18-3
blur_circular Chemical Specifications
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Molecular Information
Weight
271.24 g/mol
Formula
C₁₃H₁₂F₃NO₂
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Registry Numbers
MDL Number
MFCD25542358
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in the synthesis of fluoroquinolone antibiotics, this compound plays a key role in pharmaceutical development due to the presence of the trifluoromethyl group, which enhances metabolic stability and bioavailability. Its structure supports the formation of core quinolone scaffolds important for antimicrobial activity. It is primarily employed in research settings for developing new agents against bacterial infections, especially those involving resistant strains. Additionally, it serves as a building block in medicinal chemistry for optimizing drug candidates targeting DNA gyrase and topoisomerase IV.
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