Ranitidine base is primarily used in the treatment and management of gastrointestinal conditions. It is commonly prescribed to reduce stomach acid production, making it effective in treating ulcers in the stomach and intestines. It is also used to manage gastroesophageal reflux disease (GERD), providing relief from symptoms like heartburn and acid indigestion. Additionally, it is utilized in the treatment of Zollinger-Ellison syndrome, a condition characterized by excessive stomach acid production. Ranitidine base can also be administered to prevent stress ulcers in critically ill patients and to manage conditions where acid reduction is necessary for healing. Its ability to block histamine receptors in the stomach lining makes it a key component in acid-related disorder therapies.