Rebamipide is primarily used in the treatment of gastric and duodenal ulcers and gastritis. It works by promoting the healing of the gastric mucosa, enhancing the production of prostaglandins, and increasing the mucus secretion in the stomach lining. This helps to protect the stomach from further damage caused by factors such as acid, pepsin, and other irritants. Additionally, rebamipide is effective in managing conditions like gastric lesions induced by nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori-associated gastritis. It is also used in the treatment of recurrent aphthous stomatitis, a condition characterized by painful mouth ulcers, and in managing reflux esophagitis or gastroesophageal reflux disease (GERD). Furthermore, rebamipide has shown promise in improving symptoms of dry eye syndrome by promoting corneal and conjunctival epithelial healing and reducing inflammation. Its anti-inflammatory and mucosal protective properties make it a versatile therapeutic agent in gastrointestinal and ocular health.