Pre-Tocopherol (Delta-tocopherol glucoside)

Pre-Tocopherol (Delta-tocopherol glucoside)
Cosmetics Code: 126142

Tocopherol glucoside is widely used in most Avene's product as core active ingredient

(delta type - the most effective form for skin)

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Pre-Tocopherol (Delta-tocopherol glucoside)

Tocopherol glucoside is widely used in most Avene's product as core active ingredient

(delta type - the most effective form for skin)

Pre-Tocopherol (Delta-tocopherol glucoside) is a derivative of delta-tocopherol, a form of vitamin E. It is conjugated with glucose to form a glucoside, which can enhance its stability and water solubility compared to free tocopherol.

Tocopherol glucoside is widely used in most Avene's product as core active ingredient.


Below are some key points about delta-tocopherol glucoside:

Characteristics:

  1. Molecular Structure: A glucose molecule is attached to delta-tocopherol, making it a glucoside derivative.
  2. Increased Stability: The glucoside form protects the tocopherol from oxidation, extending its shelf life and making it suitable for formulations.
  3. Water Solubility: The glucoside modification improves water solubility, enabling better incorporation into aqueous systems like emulsions or hydrogels.

Applications:

  1. Cosmetics:
    • Antioxidant Properties: Provides protection against oxidative stress, helping to stabilize formulations and protect skin cells from free radical damage.
    • Skin Brightening: May contribute to a brightening effect due to its ability to interact with cellular mechanisms.
    • Anti-Aging: Works as a scavenger of free radicals, reducing signs of aging such as wrinkles and fine lines.
  2. Nutraceuticals: Potential for use in dietary supplements for enhanced bioavailability and antioxidant benefits.
  3. Pharmaceuticals: May have applications in formulations requiring stable, water-soluble forms of vitamin E derivatives.

Enzymatic Conversion in Skin:

When applied topically, delta-tocopherol glucoside can be enzymatically hydrolyzed by skin enzymes (e.g., glucosidases), releasing active delta-tocopherol. This makes it a pro-antioxidant that activates upon contact with the skin.

Benefits Over Regular Tocopherols:

 

Use: Can be used in all kinds of Anti-aging products.

Mixing method: Mix in the water-phase, if you need to use above 0.01%, suggest to add small amount of ethanol (1-2%) in the formulation to help fully dissolve

Usage rate: 0.05-0.1%

Product characteristics: Light colored powder

Solubility: can dissolve in water (at about 0.05%), can freely dissolve in ethanol

Storage: For long term storage Store in the refrigerator at temperature 5. °C avoid light At least 3 years old

 

INCI Name : Tocopherol glucoside

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