Used topically to treat inflammatory skin conditions such as atopic dermatitis (eczema), particularly in patients who do not respond well to other therapies. It works by suppressing local immune responses in the skin, reducing inflammation and itching without the side effects associated with long-term corticosteroid use. Due to its targeted action, it is suitable for sensitive areas like the face and neck. Pimecrolimus is often prescribed for short-term and intermittent long-term management to prevent flare-ups.