Physalin D exhibits significant anti-inflammatory and immunomodulatory properties, making it a compound of interest in therapeutic research. It has demonstrated potent activity in suppressing pro-inflammatory cytokines, which may be beneficial in treating chronic inflammatory diseases. Studies suggest potential in cancer research due to its ability to induce apoptosis in certain tumor cell lines. Additionally, Physalin D shows antiviral effects, particularly against herpes simplex virus and hepatitis B virus, indicating possible use in antiviral drug development. Its bioactivity also extends to antimicrobial applications, where it inhibits the growth of several pathogenic microorganisms. Due to these diverse biological activities, Physalin D is primarily investigated as a lead compound for developing novel pharmaceutical agents.