Macedonic acid is primarily used in research settings for its potential anti-inflammatory and anticancer properties. It has shown activity in inhibiting certain enzymes involved in inflammatory pathways, making it a compound of interest in the development of pharmaceuticals targeting chronic inflammation and related diseases. Studies also indicate that macedonic acid can induce apoptosis in specific cancer cell lines, suggesting its utility in oncology research. Additionally, it serves as a natural product scaffold for synthesizing derivatives with enhanced biological activity. Its presence in some medicinal plants further supports its role in traditional medicine validation and phytochemical analysis.