14-Deoxy-12-hydroxyandrographolide is a derivative of andrographolide, investigated in pharmacological and biochemical research for its anti-inflammatory and antiviral properties. It shows potential in managing respiratory infections by reducing mucus secretion and easing cough. Studies have explored its liver-protective effects, particularly against drug-induced or alcohol-related liver damage. The compound exhibits immunomodulatory activity, helping to regulate immune responses. Preliminary research also indicates anticancer potential due to its ability to induce apoptosis in certain cancer cell lines. Commonly used in in vitro and in vivo experiments to assess efficacy, toxicity, and mechanisms of action, with potential as a lead compound for drug development.