Chlorantholide A exhibits significant anti-inflammatory properties by inhibiting the production of pro-inflammatory mediators such as nitric oxide and cytokines in activated macrophages. This makes it a candidate for research into treatments for chronic inflammatory diseases. It also shows neuroprotective effects in cellular models, suggesting potential use in neurodegenerative disorder studies, including Alzheimer’s and Parkinson’s diseases. Additionally, Chlorantholide A has demonstrated mild cytotoxic activity against certain cancer cell lines, prompting interest in its role as a lead compound for anticancer drug development. Its natural origin and biological activity profile support its use in pharmacological studies focused on immune modulation and cell protection mechanisms.