Carmichaenine E is primarily investigated for its potential biological activity, particularly in anti-inflammatory and neuroprotective applications. It has shown promise in early-stage research for modulating cellular pathways involved in oxidative stress and neuronal damage, suggesting possible utility in neurodegenerative disease models such as Alzheimer’s and Parkinson’s. Additionally, it exhibits mild antimicrobial properties against select bacterial strains, making it a candidate for further exploration in antimicrobial agent development. Due to its natural origin and structural complexity, it is also used as a reference compound in phytochemical profiling and metabolite studies of plant extracts, especially in chemotaxonomic research.