Used in research for its potential anti-inflammatory, antispasmodic, and neuroprotective properties. It exhibits activity in modulating cellular pathways related to oxidative stress, inhibiting smooth muscle contraction, and supporting neuronal health in experimental models. Investigated for applications in treating neurodegenerative conditions, as well as respiratory and circulatory disorders. Also valued in natural product chemistry for its structural complexity as a sesquiterpene lactone derived from medicinal plants such as Petasites species, and employed in structure-activity relationship studies of plant-derived lactones.