Auranofin is primarily used in the treatment of rheumatoid arthritis, particularly in patients who have not responded adequately to other therapies. It helps reduce inflammation and joint damage by modulating the immune response. Beyond its use in arthritis, auranofin has shown potential in cancer research, where it is being studied for its ability to induce apoptosis in certain cancer cells. Additionally, it has been explored for its antimicrobial properties, particularly against parasitic infections like amoebiasis. Its unique mechanism of action, involving the inhibition of thioredoxin reductase, makes it a promising candidate for repurposing in various therapeutic areas.