Diethyl 2-[2-fluoro-4-biphenyl-4-yl]-2-methylmalonate is primarily used as an intermediate in the synthesis of various organic compounds. It plays a significant role in the production of pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs). Its structure allows it to be a key building block in creating molecules that exhibit anti-inflammatory and analgesic properties. Additionally, it is utilized in research and development for designing new chemical entities with potential therapeutic applications. Its fluorine and biphenyl components make it valuable in optimizing drug efficacy and selectivity.