Polmacoxib is primarily used in veterinary medicine as a nonsteroidal anti-inflammatory drug (NSAID) to manage pain and inflammation associated with musculoskeletal disorders in animals, particularly dogs. It works by selectively inhibiting the COX-2 enzyme, which is responsible for inflammation and pain, while sparing the COX-1 enzyme that protects the stomach lining. This selective action helps reduce the risk of gastrointestinal side effects commonly seen with non-selective NSAIDs. Polmacoxib is often prescribed for conditions such as osteoarthritis, providing relief from joint pain and improving mobility in affected animals. Its efficacy and safety profile make it a valuable option for long-term management of chronic inflammatory conditions in pets.