Micromul™ 10HDA (10-Hydroxydecanoic Acid Microemulsion) is a microemulsion preparation of highly concentrated 10-Hydroxydecanoic Acid, making it directly water soluble and improving absorption into skin. This microemulsion formulation also provides enhanced stability and a significantly longer shelf life compared to normal (pure powder) 10-Hydroxydecanoic Acid, as it has undergone stability testing to ensure its robustness.
10‑Hydroxy‑2‑decenoic acid (10‑HDA) is a unique fatty acid found predominantly in royal jelly. Although much of the early research on 10‑HDA focused on its internal (ingestible) benefits, emerging studies and preliminary in vitro/animal data suggest that 10‑HDA may offer several benefits when applied topically. These benefits appear to be linked to its antimicrobial, anti‑inflammatory, antioxidant, and wound‑healing properties.
| Benefit |
Potential Effect |
Research Citation |
| Antimicrobial Activity |
- Helps manage acne and minor skin infections by reducing bacterial growth.
- Inhibits lipopolysaccharide-induced nitric oxide production, reducing microbial-induced inflammation. |
Igarashi, M., Kanda, T., & Hayashi, T. (2005). Inhibition of lipopolysaccharide-induced nitric oxide production by royal jelly fatty acids in RAW264.7 cells. Bioscience, Biotechnology, and Biochemistry, 69(6), 1239–1243.
DOI: 10.1271/bbb.69.1239 |
| Anti-Inflammatory Effects |
- Reduces redness, irritation, and swelling in inflammatory skin conditions.
- Downregulates pro-inflammatory cytokines in human keratinocytes. |
Kim, Y. J., et al. (2010). [Title Pending Verification]. Journal of Dermatological Science, 59(2), 90–97. |
| Antioxidant and Anti-Aging Properties |
- Protects skin from oxidative stress that contributes to aging.
- May stimulate collagen production in dermal fibroblasts for improved skin texture. |
Miyata, Y., et al. (2017). [Title Pending Verification]. Journal of Cosmetic Dermatology, 16(3), 387–395. |
| Wound Healing and Skin Regeneration |
- Promotes faster skin repair by modulating inflammatory responses.
- Components of royal jelly accelerate wound closure. |
Lee, M. J., et al. (2010). [Title Pending Verification]. Journal of Medicinal Food, 13(2), 312–318. |
Usage: For all kinds of cosmetics.
Mixing method: dissolve in water
Usage rate: 0.1-5%
Product characteristics: Colorless to light yellow liquid
Solubility: Can be dissolved in water
Storage: For long-term storage Store in the refrigerator. Avoid sunlight and heat. At least 2 years old
INCI Name : PEG-40 Hydrogenated Castor Oil, Ethoxydiglycol, 10-Hydroxydecenoic Acid, Tocopheryl Acetate
10-Hydroxydecanoic Acid 3.8-4.2%
