Cyclo(Pro-Leu) is a cyclic dipeptide primarily used in biochemical and pharmaceutical research to study the structure and function of cyclic peptides, which offer higher stability than linear peptides. It serves as a model for investigating peptide folding and interactions with target proteins in biological systems, and holds potential as a bioactive compound, such as an antimicrobial agent or enzyme inhibitor. Additionally, it is incorporated into cosmetic formulations for its skin-conditioning properties, helping to improve skin texture and hydration. In anti-aging products, it supports skin elasticity and reduces the appearance of fine lines. The compound is also explored for promoting wound healing and modulating inflammatory responses in dermatological applications. Its stability and compatibility with various formulation types make it suitable for creams, serums, and lotions.