4-Chloro-3-fluoro-2-iodoaniline is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its unique halogen substitution pattern makes it valuable for constructing complex molecules, especially in the development of active pharmaceutical ingredients (APIs). It is often employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig reactions, to create biologically active compounds. Additionally, it serves as a building block in the synthesis of herbicides and fungicides, contributing to crop protection strategies. Its role in medicinal chemistry includes the development of potential drug candidates targeting various diseases.