2-Methoxy-5-nitrobenzene-1,4-diamine is primarily used as an intermediate in the formulation of oxidative hair dyes, serving as a coupler to produce permanent, vibrant, and long-lasting color shades, particularly brown tones, when combined with developers like p-phenylenediamine. Its structure with nitro and amino groups enables effective coupling reactions in alkaline conditions. Additionally, it finds applications in the synthesis of other dyes and pigments for cosmetics and potentially in organic synthesis for pharmaceutical intermediates, acting as a versatile building block due to its reactive functional groups.