4-Chloro-(N-Boc)aniline
97%
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description Product Description
Widely used in organic synthesis, particularly in pharmaceutical and agrochemical industries, as a protected aniline derivative. The Boc (tert-butoxycarbonyl) group provides stability and selectivity during multi-step reactions by preventing unwanted side reactions at the amine site. The presence of the chlorine substituent allows for further functionalization through cross-coupling reactions such as Suzuki, Heck, or Buchwald-Hartwig aminations. Commonly employed as an intermediate in the preparation of active pharmaceutical ingredients (APIs), where controlled deprotection of the Boc group enables the formation of secondary or tertiary amines. Its balanced reactivity and ease of purification make it a preferred building block in medicinal chemistry and process development.
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