5-(Benzyloxy)-2-bromo-4-methylaniline
≥95%
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and anti-cancer compounds. The structure features an aniline core with a bromo group at the 2-position, a methyl group at the 4-position, and a benzyloxy group at the 5-position, enabling selective functionalization and diverse transformations such as nucleophilic substitutions, cross-coupling reactions (e.g., Suzuki-Miyaura for biaryl formation or Buchwald-Hartwig amination for arylamine linkages), and deprotection of the benzyloxy moiety. This makes it valuable for building complex molecules in drug discovery. Additionally, it is employed in the preparation of agrochemicals and functional dyes, leveraging its reactive bromo and aniline functionalities.
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