tert-Butyl (2-(4-aminophenyl)-2-methylpropyl)carbamate
97%
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description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) where selective protection of amine groups is required. The tert-butyl carbamate (Boc) group protects the aliphatic primary amine, enabling selective reactions at the free aromatic amine (4-aminophenyl) during multi-step syntheses. After desired transformations, the Boc group can be removed to reveal the aliphatic amine for further functionalization, such as in amide bond formation. This compound is valuable in preparing analgesics, anti-inflammatory agents, and other bioactive molecules. Its branched structure introduces sterically hindered groups that enhance metabolic stability and binding affinity in final drug compounds. Commonly used in R&D to optimize synthetic routes and yields for aromatic amine-based and heterocyclic pharmaceuticals.
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