4-(Trimethylsilyl)aniline is utilized as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials such as liquid crystals and organic semiconductors. The trimethylsilyl substituent on the aromatic ring modulates the electronic properties of the aniline moiety, enhancing solubility in nonpolar solvents and enabling selective transformations. It is commonly employed in cross-coupling reactions, particularly Hiyama-Denmark coupling, where the C-Si bond is activated to form new carbon-carbon bonds in complex aromatic structures. Additionally, its volatility and reactivity suit it for vapor-phase deposition techniques and surface functionalization in materials science applications.