4-(tetrazol-1-yl)benzoic acid
96%
Reagent
Code: #244102
CAS Number
78190-05-3
blur_circular Chemical Specifications
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Molecular Information
Weight
190.16 g/mol
Formula
C₈H₆N₄O₂
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Registry Numbers
MDL Number
MFCD00574246
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Physical Properties
Boiling Point
423.3 °C at 760 mmHg
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Storage & Handling
Density
1.53 g/cm3
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological activity, enhancing binding to the AT1 receptor. Also employed in coordination chemistry to form metal-organic frameworks (MOFs) due to its ability to act as a multidentate ligand. Additionally, finds use in medicinal chemistry for developing new bioactive compounds with potential anti-inflammatory or anticancer properties.
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