2-(2-(((tert-butoxycarbonyl)amino)methyl)-[1,1-biphenyl]-2-yl)acetic acid
95%
Reagent
Code: #242920
CAS Number
158066-12-7
blur_circular Chemical Specifications
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Molecular Information
Weight
341.40 g/mol
Formula
C₂₀H₂₃NO₄
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Registry Numbers
MDL Number
MFCD23378431
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Physical Properties
Boiling Point
555.4±50.0 °C(Predicted)
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Storage & Handling
Density
1.163±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of valsartan and related sartans. The biphenyl core with protected aminomethyl and acetic acid groups facilitates efficient coupling reactions to build the essential biaryl-tetrazole scaffold. Commonly employed in research and industrial settings for developing antihypertensive medications. The Boc protecting group allows selective deprotection in multi-step syntheses, ensuring high purity and yield.
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