5-(m-Tolyl)-1H-tetrazole
98%
science Other reagents with same CAS 3441-00-7
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan, valsartan, and irbesartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor while improving metabolic stability and oral bioavailability. Commonly employed in pharmaceutical research and development for constructing bioisosteres in drug design. Also utilized in coordination chemistry as a ligand for metal ions due to its nitrogen-rich structure.
shopping_cart Available Sizes & Pricing
Cart
No products