5-(m-Tolyl)-1H-tetrazole

98%

Reagent Code: #242582
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CAS Number 3441-00-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 160.18 g/mol
Formula C₈H₈N₄
badge Registry Numbers
MDL Number MFCD03093096
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan, valsartan, and irbesartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor while improving metabolic stability and oral bioavailability. Commonly employed in pharmaceutical research and development for constructing bioisosteres in drug design. Also utilized in coordination chemistry as a ligand for metal ions due to its nitrogen-rich structure.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿168.00
inventory 1g
10-20 days ฿486.00
inventory 5g
10-20 days ฿2,406.00

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