Triphenyl methyl olmesartan
99%
science Other reagents with same CAS 144690-92-6
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description Product Description
Used in the synthesis of olmesartan medoxomil, an angiotensin II receptor blocker (ARB) prescribed for the treatment of hypertension. It serves as a key intermediate in the preparation of the active pharmaceutical ingredient, where the triphenylmethyl protecting group facilitates selective reactions, enabling the formation of the ester prodrug that enhances oral bioavailability. The core structure derived from this intermediate allows for selective binding to the AT1 receptor, contributing to the drug’s efficacy in lowering blood pressure. Widely utilized in pharmaceutical manufacturing processes due to its stability and reactivity profile in esterification and protection-deprotection steps.
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