Triphenyl methyl olmesartan
99%
Reagent
Code: #239085
CAS Number
144690-92-6
blur_circular Chemical Specifications
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Molecular Information
Weight
800.90 g/mol
Formula
C₄₈H₄₄N₆O₆
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Registry Numbers
MDL Number
MFCD08704231
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Physical Properties
Boiling Point
960°C at 760 mmHg
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Storage & Handling
Storage
Room temperature, airtight, dry
description Product Description
Used in the synthesis of olmesartan medoxomil, an angiotensin II receptor blocker (ARB) prescribed for the treatment of hypertension. It serves as a key intermediate in the preparation of the active pharmaceutical ingredient, where the triphenylmethyl protecting group facilitates selective reactions, enabling the formation of the ester prodrug that enhances oral bioavailability. The core structure derived from this intermediate allows for selective binding to the AT1 receptor, contributing to the drug’s efficacy in lowering blood pressure. Widely utilized in pharmaceutical manufacturing processes due to its stability and reactivity profile in esterification and protection-deprotection steps.
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