(S)-3-((tert-Butoxycarbonyl)amino)-3-(2,3-dichlorophenyl)propanoic acid
98%
Reagent
Code: #233325
CAS Number
499995-82-3
blur_circular Chemical Specifications
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Molecular Information
Weight
334.2 g/mol
Formula
C₁₄H₁₇Cl₂NO₄
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Registry Numbers
MDL Number
MFCD03427905
thermostat
Physical Properties
Boiling Point
468.9±45.0 °C(Predicted)
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Storage & Handling
Density
1.321±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry enables selective binding and improved pharmacokinetic properties in the final drug substance. The Boc-protected amine and carboxylic acid functional groups allow for stepwise peptide-like coupling and deprotection strategies in multi-step organic synthesis. Commonly employed in pharmaceutical research and development for building complex molecules requiring high enantiomeric purity.
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