(S)-3-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid
95%
Reagent
Code: #232427
CAS Number
1241681-36-6
blur_circular Chemical Specifications
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Molecular Information
Weight
334.2 g/mol
Formula
C₁₄H₁₇Cl₂NO₄
thermostat
Physical Properties
Boiling Point
475.8±45.0 °C(Predicted)
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Storage & Handling
Density
1.321±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry enables selective interaction with biological targets, improving drug efficacy and reducing side effects. Commonly employed in pharmaceutical research and development for constructing peptidomimetic structures due to the protected amine and carboxylic acid functionalities, allowing for sequential coupling reactions in multi-step syntheses.
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