(R)-2-(6-((2’,6’-Dimethyl-4’-(3-(Methylsulfonyl)Propoxy)-[1,1’-Biphenyl]-3-Yl)Methoxy)-2,3-Dihydrobenzofuran-3-Yl)Acetic Acid

95%

Reagent Code: #231648
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CAS Number 1234474-57-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 524.63 g/mol
Formula C₂₉H₃₂O₇S
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used primarily as a key intermediate in the development of angiotensin II receptor antagonists for the treatment of hypertension. Its structural properties contribute to high selectivity and binding affinity to the AT1 receptor in the final drug, promoting effective blood pressure control. The compound is designed to improve metabolic stability and oral bioavailability of the resulting medications, making them suitable for once-daily dosing in antihypertensive treatments. It also contributes to reducing the risk of cardiovascular events in patients with chronic high blood pressure. Its methylsulfonyl-containing side chain enhances solubility and pharmacokinetic profile of the drug, supporting formulation in tablet dosage forms.

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Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿58,500.00

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