(R)-Methyl 5-(6-(Pivaloyloxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate

98%

Reagent Code: #231581
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CAS Number 929095-38-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 560.58 g/mol
Formula C₂₈H₂₇F₃N₂O₅S
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as an intermediate in the synthesis of angiotensin II receptor antagonists for the treatment of hypertension. Shows high efficacy in blocking the AT1 receptor subtype, contributing to reduced blood pressure. Its structure allows for improved metabolic stability and oral bioavailability in pharmaceutical formulations. Employed in the development of prodrugs due to the presence of ester and pivaloyloxymethyl groups, which enhance intestinal absorption and facilitate in vivo hydrolysis to the active form. Also investigated for use in combination therapies targeting cardiovascular diseases.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿38,290.00
inventory 250mg
10-20 days ฿63,820.00

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