(R)-3-([1,1'-Biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid
95%
Reagent
Code: #230121
CAS Number
128779-47-5
blur_circular Chemical Specifications
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Molecular Information
Weight
341.4 g/mol
Formula
C₂₀H₂₃NO₄
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Registry Numbers
MDL Number
MFCD00191185
thermostat
Physical Properties
Boiling Point
528.2°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key chiral intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its stereochemistry allows for selective interaction with biological targets, enhancing drug efficacy. The Boc-protected amine and carboxylic acid functionalities enable stepwise peptide-like coupling in multi-step organic syntheses, making it valuable in pharmaceutical development for cardiovascular therapies.
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