5-(3-Phenylpropyl)-1H-1,2,3,4-tetrazole
95%
Reagent
Code: #223262
CAS Number
197447-36-2
science Other reagents with same CAS 197447-36-2
blur_circular Chemical Specifications
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Molecular Information
Weight
188.23 g/mol
Formula
C₁₀H₁₂N₄
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the AT1 receptor. Commonly employed in pharmaceutical research for optimizing drug candidates targeting cardiovascular diseases. Also utilized in the preparation of functionalized heterocyclic compounds for medicinal chemistry and drug discovery programs.
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