N-(3-(5-Mercapto-1H-tetrazol-1-yl)phenyl)acetamide

98%

Reagent Code: #217455
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CAS Number 14070-48-5

science Other reagents with same CAS 14070-48-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 235.27 g/mol
Formula C₉H₉N₅OS
badge Registry Numbers
MDL Number MFCD00603728
thermostat Physical Properties
Melting Point 185-187°C
inventory_2 Storage & Handling
Density 1.51g/mL
Storage Room temperature, dry

description Product Description

Used as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. The thiol group allows for further chemical modifications, making it valuable in medicinal chemistry for creating derivatives with improved pharmacokinetic properties. Also employed in research for developing new cardiovascular medications and in the preparation of radiolabeled compounds for drug metabolism studies.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿830.00
inventory 5g
10-20 days ฿3,700.00

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N-(3-(5-Mercapto-1H-tetrazol-1-yl)phenyl)acetamide
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Used as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. The thiol group allows for further chemical modifications, making it valuable in medicinal chemistry for creating derivatives with improved pharmacokinetic properties. Also employed in research for developing new cardiovas

Used as an intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. The thiol group allows for further chemical modifications, making it valuable in medicinal chemistry for creating derivatives with improved pharmacokinetic properties. Also employed in research for developing new cardiovascular medications and in the preparation of radiolabeled compounds for drug metabolism studies.

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