5-[2-(4-Methylbiphenyl)]Tetrazole

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Reagent Code: #212746
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CAS Number 120568-11-8

science Other reagents with same CAS 120568-11-8

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Weight 236.27 g/mol
Formula C₁₄H₁₂N₄
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Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like candesartan and related sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. This compound plays a critical role in improving the potency and metabolic stability of these drugs. It is also employed in medicinal chemistry research for developing new bioactive molecules due to its favorable pharmacokinetic properties and ability to increase water solubility of drug candidates.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,830.00
inventory 250mg
10-20 days ฿11,380.00
inventory 1g
10-20 days ฿27,920.00

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5-[2-(4-Methylbiphenyl)]Tetrazole
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Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like candesartan and related sartan-class medications. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. This compound plays a critical role in improving the potency and metabolic stability of these drugs. It is also employed in medicinal chemistry research for developing new bioactive molecules due to its favorable pharmacokinetic properties and ability to increase water solubility of drug candidates.
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