5-(4-Methoxyphenyl)-2H-tetrazole
95%
Reagent
Code: #210138
CAS Number
6926-51-8
science Other reagents with same CAS 6926-51-8
blur_circular Chemical Specifications
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Molecular Information
Weight
176.18 g/mol
Formula
C₈H₈N₄O
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Registry Numbers
MDL Number
MFCD00991875
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like losartan and candesartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Shows potential in the development of new pharmaceuticals due to its ability to participate in hydrogen bonding and dipole interactions with biological targets.
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