5-(2-Methoxyphenyl)-1H-tetrazole

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Reagent Code: #210136
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CAS Number 51449-81-1

science Other reagents with same CAS 51449-81-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 176.18 g/mol
Formula C₈H₈N₄O
badge Registry Numbers
MDL Number MFCD03093093
inventory_2 Storage & Handling
Storage Room temperature, airtight, dry

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like losartan and candesartan. Its structure, serving as a pharmacophore, enables effective binding to the angiotensin II receptor (e.g., AT1 receptor in the renin-angiotensin system), making it valuable in developing specific medications for high blood pressure and heart-related conditions with reduced side effects. Additionally, it is used as a starting material for synthesizing derivatives with anti-inflammatory, antimicrobial, and anticancer activities in medicinal chemistry research. Also employed in coordination chemistry as a ligand due to its nitrogen-rich heterocyclic framework, supporting the formation of metal-organic complexes with potential catalytic or material applications.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,112.00
inventory 1g
10-20 days ฿5,313.00
inventory 5g
10-20 days ฿33,790.00

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5-(2-Methoxyphenyl)-1H-tetrazole
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Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like losartan and candesartan. Its structure, serving as a pharmacophore, enables effective binding to the angiotensin II receptor (e.g., AT1 receptor in the renin-angiotensin system), making it valuable in developing specific medications for high blood pressure and heart-related conditions with reduced side effects. Additionally, it is used as a starti

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like losartan and candesartan. Its structure, serving as a pharmacophore, enables effective binding to the angiotensin II receptor (e.g., AT1 receptor in the renin-angiotensin system), making it valuable in developing specific medications for high blood pressure and heart-related conditions with reduced side effects. Additionally, it is used as a starting material for synthesizing derivatives with anti-inflammatory, antimicrobial, and anticancer activities in medicinal chemistry research. Also employed in coordination chemistry as a ligand due to its nitrogen-rich heterocyclic framework, supporting the formation of metal-organic complexes with potential catalytic or material applications.

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