5-(2-Methoxyphenyl)-1H-tetrazole
98%
science Other reagents with same CAS 51449-81-1
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description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like losartan and candesartan. Its structure, serving as a pharmacophore, enables effective binding to the angiotensin II receptor (e.g., AT1 receptor in the renin-angiotensin system), making it valuable in developing specific medications for high blood pressure and heart-related conditions with reduced side effects. Additionally, it is used as a starting material for synthesizing derivatives with anti-inflammatory, antimicrobial, and anticancer activities in medicinal chemistry research. Also employed in coordination chemistry as a ligand due to its nitrogen-rich heterocyclic framework, supporting the formation of metal-organic complexes with potential catalytic or material applications.
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