Methyl 3-(1H-tetrazol-5-yl)propanoate
95%
science Other reagents with same CAS 134558-05-7
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. The tetrazole ring mimics the carboxylic acid group in biological activity, enhancing binding to the angiotensin II receptor. Its ester functionality allows for easy modification during multi-step drug synthesis. Commonly employed in pharmaceutical research and development for optimizing drug candidates targeting cardiovascular diseases.
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