Losartan Carboxylic Acid
10mM in DMSO
Reagent
Code: #201891
CAS Number
124750-92-1
science Other reagents with same CAS 124750-92-1
blur_circular Chemical Specifications
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Molecular Information
Weight
436.89 g/mol
Formula
C₂₂H₂₁ClN₆O₂
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Storage & Handling
Storage
-20°C
description Product Description
Used as an active metabolite of losartan, it acts as a selective angiotensin II receptor blocker (ARB). It is primarily employed in the treatment of hypertension by inhibiting the vasoconstrictor and aldosterone-secreting effects of angiotensin II, leading to reduced blood pressure. It also provides renal protection in diabetic patients and is used in managing chronic heart failure. Its action helps delay the progression of diabetic nephropathy by reducing proteinuria and maintaining glomerular filtration rate.
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