2-[3-(1h-1,2,3,4-tetrazol-1-yl)phenoxy]propanoicacid
98%
science Other reagents with same CAS 832739-85-2
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like candesartan and azilsartan. Its tetrazole ring mimics the carboxylic acid group in peptide structures, enhancing binding affinity to the angiotensin II receptor. This compound plays a critical role in improving the potency and metabolic stability of these medications. It is also employed in medicinal chemistry research for developing new bioactive molecules targeting cardiovascular diseases.
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