3-(1H-1,2,3,4-Tetrazol-1-yl)phenol
98%
Reagent
Code: #197401
CAS Number
125620-16-8
blur_circular Chemical Specifications
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Molecular Information
Weight
162.15 g/mol
Formula
C₇H₆N₄O
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Registry Numbers
MDL Number
MFCD01860802
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like losartan and candesartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the AT1 receptor. Also employed in coordination chemistry as a ligand for metal ions due to the nitrogen-rich tetrazole moiety, useful in the development of metal-organic frameworks (MOFs) and catalytic systems. Additionally, finds use in agrochemicals as a building block for herbicides and plant growth regulators.
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