3-(1H-1,2,3,4-Tetrazol-1-yl)phenol
98%
science Other reagents with same CAS 125620-16-8
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description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like losartan and candesartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the AT1 receptor. Also employed in coordination chemistry as a ligand for metal ions due to the nitrogen-rich tetrazole moiety, useful in the development of metal-organic frameworks (MOFs) and catalytic systems. Additionally, finds use in agrochemicals as a building block for herbicides and plant growth regulators.
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