2-(1H-Tetrazol-5-Yl)Benzonitrile
97%
science Other reagents with same CAS 71515-74-7
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description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like valsartan and losartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Commonly employed in pharmaceutical research and development for designing potent and selective cardiovascular medications. Also utilized in the preparation of other bioactive molecules where tetrazole functionality is required for improved metabolic stability and oral bioavailability.
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