Used in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like azilsartan and related sartan-class medications. The tetrazole ring acts as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving receptor binding affinity. Its lipophilic trifluoromethylpyridine moiety contributes to increased membrane permeability and prolonged pharmacological activity. Commonly employed in pharmaceutical research and development for optimizing drug candidates targeting hypertension and cardiovascular diseases.