5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole
98%
blur_circular Chemical Specifications
description Product Description
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Its bromo-substituted biphenyl structure allows for further functionalization through cross-coupling reactions, making it a valuable intermediate in medicinal chemistry for drug design and optimization.
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| Test Parameter | Specification |
|---|---|
| Appearance | White solid |
| Purity (%) | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
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