5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole

98%

Reagent Code: #195703

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 301.15 g/mol
Formula C₁₃H₉BrN₄
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Its bromo-substituted biphenyl structure allows for further functionalization through cross-coupling reactions, making it a valuable intermediate in medicinal chemistry for drug design and optimization.

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Test Parameter Specification
Appearance White solid
Purity (%) 97.5-100%
Infrared Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿913.00
inventory 250mg
10-20 days ฿2,772.00
inventory 1g
10-20 days ฿14,400.00
inventory 5g
10-20 days ฿46,800.00

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5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole
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Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Its bromo-substituted biphenyl structure allows for further functionalization through cross-coupling reactions, making it a valuable intermediate in medicinal chemistry for drug design and optimization.

Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Its bromo-substituted biphenyl structure allows for further functionalization through cross-coupling reactions, making it a valuable intermediate in medicinal chemistry for drug design and optimization.

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