(4-(2H-Tetrazol-5-yl)phenyl)methanamine hydrochloride
97%
science Other reagents with same CAS 177595-28-7
blur_circular Chemical Specifications
description Product Description
Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like losartan and valsartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving antihypertensive activity. Its amine functionality allows for easy derivatization, making it valuable in drug development for cardiovascular diseases. Also employed in research for designing new bioactive molecules due to the metabolic stability and polarity provided by the tetrazole ring.
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