(4-(2H-Tetrazol-5-yl)phenyl)methanamine hydrochloride

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Reagent Code: #195651
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CAS Number 177595-28-7

science Other reagents with same CAS 177595-28-7

blur_circular Chemical Specifications

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Weight 211.65 g/mol
Formula C₈H₁₀ClN₅
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MDL Number MFCD28399426
inventory_2 Storage & Handling
Storage Store in an inert gas at room temperature

description Product Description

Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like losartan and valsartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving antihypertensive activity. Its amine functionality allows for easy derivatization, making it valuable in drug development for cardiovascular diseases. Also employed in research for designing new bioactive molecules due to the metabolic stability and polarity provided by the tetrazole ring.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,100.00
inventory 250mg
10-20 days ฿9,670.00
inventory 1g
10-20 days ฿29,990.00

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(4-(2H-Tetrazol-5-yl)phenyl)methanamine hydrochloride
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Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like losartan and valsartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving antihypertensive activity. Its amine functionality allows for easy derivatization, making it valuable in drug development for cardiovascular diseases. Also employed in research for designing new bioactive molecules due to the metabolic stability

Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like losartan and valsartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving antihypertensive activity. Its amine functionality allows for easy derivatization, making it valuable in drug development for cardiovascular diseases. Also employed in research for designing new bioactive molecules due to the metabolic stability and polarity provided by the tetrazole ring.

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