1-(4-Hydroxyphenyl)-5-mercapto-1H-tetrazole

≥90%(T)

Reagent Code: #195128
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CAS Number 52431-78-4

science Other reagents with same CAS 52431-78-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 194.21 g/mol
Formula C₇H₆N₄OS
badge Registry Numbers
MDL Number MFCD00132898
thermostat Physical Properties
Melting Point 162°C(分解)
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor blockers (ARBs), particularly in the production of antihypertensive drugs like candesartan and olmesartan. Its thiol and tetrazole functional groups enhance binding affinity to the AT1 receptor, improving drug efficacy. Also employed in medicinal chemistry for developing new bioactive molecules due to its ability to mimic carboxylic acid groups while offering better metabolic stability and membrane permeability.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿550.00
inventory 25g
10-20 days ฿9,300.00
inventory 5g
10-20 days ฿1,890.00

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1-(4-Hydroxyphenyl)-5-mercapto-1H-tetrazole
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Used as a key intermediate in the synthesis of angiotensin II receptor blockers (ARBs), particularly in the production of antihypertensive drugs like candesartan and olmesartan. Its thiol and tetrazole functional groups enhance binding affinity to the AT1 receptor, improving drug efficacy. Also employed in medicinal chemistry for developing new bioactive molecules due to its ability to mimic carboxylic acid groups while offering better metabolic stability and membrane permeability.

Used as a key intermediate in the synthesis of angiotensin II receptor blockers (ARBs), particularly in the production of antihypertensive drugs like candesartan and olmesartan. Its thiol and tetrazole functional groups enhance binding affinity to the AT1 receptor, improving drug efficacy. Also employed in medicinal chemistry for developing new bioactive molecules due to its ability to mimic carboxylic acid groups while offering better metabolic stability and membrane permeability.

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