1-(4-Hydroxyphenyl)-5-mercapto-1H-tetrazole
≥90%(T)
science Other reagents with same CAS 52431-78-4
blur_circular Chemical Specifications
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor blockers (ARBs), particularly in the production of antihypertensive drugs like candesartan and olmesartan. Its thiol and tetrazole functional groups enhance binding affinity to the AT1 receptor, improving drug efficacy. Also employed in medicinal chemistry for developing new bioactive molecules due to its ability to mimic carboxylic acid groups while offering better metabolic stability and membrane permeability.
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